Deng H, Ge H, Dubey C, Losmanova T, Medová M, Konstantinidou G, Mutlu SM, Birrer FE, Brodie TM, Stroka D, Wang W, Peng RW, Dorn P, Marti TM. An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer Immunol Immunother. 2023 Dec;72(12):4457-4470. doi: 10.1007/s00262-023-03542-z. Epub 2023 Oct 5. PMID: 37796299.
Gioutsos K, Ehrenreich L, Azenha LF, Quapp CS, Kocher GJ, Lutz JA, Peischl S, Dorn P. Randomized Controlled Trial of Thresholds for Drain Removal After Anatomic Lung Resection. 2023 Annals of Thoracic Surgery.
Gioutsos K, Hayoz YJ, Dorn P. Clinical and Oncological Outcomes after Uniportal Anatomical Segmentectomy for Stage IA Non-Small Cell Lung Cancer. Medicina (Kaunas). 2023 Jun 1;59(6):1064. doi: 10.3390/medicina59061064. PMID: 37374269; PMCID: PMC10303980.
Sengupta A, Dorn A, Jamshidi M, Schwob M, Hassan W, De Maddalena LL, Hugi A, Stucki AO, Dorn P, Marti TM, Wisser O, Stucki JD, Krebs T, Hobi N, Guenat OT. A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Front Pharmacol. 2023 Mar 6;14:1114739. doi: 10.3389/fphar.2023.1114739. Erratum in: Front Pharmacol. 2023 Jun 05;14:1229313. PMID: 36959848; PMCID: PMC10029733.
Yang H, Gao Y, Xu D, Xu K, Liang SQ, Yang Z, Scherz A, Hall SRR, Forster S, Berezowska S, Yao F, Ochsenbein AF, Marti TM, Kocher GJ, Schmid RA, Dorn P, Peng RW. MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell Death Discov. 2023 Feb 10;9(1):55. doi: 10.1038/s41420-023-01307-2. PMID: 36765038; PMCID: PMC9918536.
Xu D, Liu S, Wu X, Marti TM, Dorn P, Schmid RA, Peng RW, Shu Y. Dissecting the Immunological Profiles in NSD3-Amplified LUSC through Integrative Multi-Scale Analyses. Cancers (Basel). 2022 Oct 12;14(20):4997. doi: 10.3390/cancers14204997. PMID: 36291782; PMCID: PMC9599511.
Karatkevich D, Deng H, Gao Y, Flint E, Peng RW, Schmid RA, Dorn P, Marti TM. Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. Int J Mol Sci. 2022 Oct 8;23(19):11949. doi: 10.3390/ijms231911949. PMID: 36233258; PMCID: PMC9569655.
Barut GT, Halwe NJ, Taddeo A, Kelly JN, Schön J, Ebert N, Ulrich L, Devisme C, Steiner S, Trüeb BS, Hoffmann B, Veiga IB, Leborgne NGF, Moreira EA, Breithaupt A, Wylezich C, Höper D, Wernike K, Godel A, Thomann L, Flück V, Stalder H, Brügger M, Esteves BIO, Zumkehr B, Beilleau G, Kratzel A, Schmied K, Ochsenbein S, Lang RM, Wider M, Machahua C, Dorn P, Marti TM, Funke-Chambour M, Rauch A, Widera M, Ciesek S, Dijkman R, Hoffmann D, Alves MP, Benarafa C, Beer M, Thiel V. The spike gene is a major determinant for the SARS-CoV-2 OmicronBA.1 phenotype. Nat Commun. 2022 Oct 7;13(1):5929. doi: 10.1038/s41467-022-33632-y. PMID: 36207334; PMCID: PMC9543931.
Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanova T, Urzi C, Ge H, Geest GA, Bruggmann R, Djonov V, Nuoffer JM, Vermathen P, Zamboni N, Riether C, Ochsenbein A, Peng RW, Kocher GJ, Schmid RA, Dorn P, Marti TM. Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cell Mol Life Sci. 2022 Jul 25;79(8):445. doi: 2.76 10.1007/s00018-022-04453-5. PMID: 35877003; PMCID: PMC9314287.
Kocher GJ, Koss AR, Groessl M, Schefold JC, Luedi MM, Quapp C, Dorn P, Lutz J, Cappellin L, Hutterli M, Lopez-Hilfiker FD, Al-Hurani M, Sesia SB. Electrocautery smoke exposure and efficacy of smoke evacuation systems in minimally invasive and open surgery: a prospective randomized study. Sci Rep. 2022 Mar 23;12(1):4941. doi: 10.1038/s41598-022-08970-y. PMID: 35322134; PMCID: PMC8943181.
Jesse J Lipp, Limei Wang, Haitang Yang, Feng Yao, Nathalie Harrer, Stefan Müller, Sabina Berezowska, Patrick Dorn, Thomas M Marti, Ralph A Schmid, Belazs Hegedüs, Abdallah Souabni, Sebastian Carotta, Mark A Pearson, Wolfgang Sommergruber, Greg J Kocher, Sean R R Hall Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. Oncoimmunology. doi: 10.1080/2162402X.2021.2019466 2022.
Patrick Dorn, Selina Pfister, Simone Oberhaensli, Konstantinos Gioutsos, Matthias Haenggi, Gregor J Kocher Operative versus non-operative management of rib fractures in flail chest after cardiopulmonary resuscitation manoeuvres. Interact Cardiovasc Thorac Surg. doi: 10.1093/icvts/ivac023 2022.
Zhang Yang, Shun-Qing Liang, Liang Zhao, Haitang Yang, Thomas M Marti, Balazs Hegedüs, Yanyun Gao, Bin Zheng, Chun Chen, Wenxiang Wang, Patrick Dorn, Gregor J Kocher, Ralph A Schmid, Ren-Wang Peng Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer. J Exp Clin Cancer Res. doi: 10.1186/s13046-022-02240-5 2022.
Haitang Yang, Sabina Berezowska, Patrick Dorn, Philipp Zens, Peiru Chen, Ren-Wang Peng, Thomas M Marti, Gregor J Kocher, Ralph A Schmid, Sean R R Hall Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. Theranostics. doi: 10.7150/thno.61209 2022.
