Kiener M, Roldan N, Machahua C, Sengupta A, Geiser T, Guenat OT, Funke-Chambour M, Hobi N, Kruithof-de Julio M. Human-Based Advanced in vitro Approaches to Investigate Lung Fibrosis and Pulmonary Effects of COVID-19. Front Med (Lausanne). 2021 May 7;8:644678. doi: 10.3389/fmed.2021.644678. PMID: 34026781; PMCID: PMC8139419..
Karkampouna, S., La Manna, F., Benjak, A. et al. Patient-derived xenografts and organoids model therapy response in prostate cancer. Nat Commun 12, 1117 (2021). https://doi.org/10.1038/s41467-021-21300-6
Karkampouna, S.; De Filippo, M.R.; Ng, C.K.Y.; Klima, I.; Zoni, E.; Spahn, M.; Stein, F.; Haberkant, P.; Thalmann, G.N.; Kruithof-de Julio, M. Stroma Transcriptomic and Proteomic Profile of Prostate Cancer Metastasis Xenograft Models Reveals Prognostic Value of Stroma Signatures. Cancers 2020, 12, 3786. https://doi.org/10.3390/cancers12123786
Minoli, M.; Kiener, M.; Thalmann, G.N.; Kruithof-de Julio, M.; Seiler, R. Evolution of Urothelial Bladder Cancer in the Context of Molecular Classifications. Int. J. Mol. Sci. 2020, 21, 5670. https://doi.org/10.3390/ijms21165670
Bonollo, F.; Thalmann, G.N.; Kruithof-de Julio, M.; Karkampouna, S. The Role of Cancer-Associated Fibroblasts in Prostate Cancer Tumorigenesis. Cancers 2020, 12, 1887. https://doi.org/10.3390/cancers12071887
Rodrigues Sousa E, Zoni E, Karkampouna S, La Manna F, Gray PC, De Menna M, Kruithof-de Julio M. A Multidisciplinary Review of the Roles of Cripto in the Scientific Literature Through a Bibliometric Analysis of its Biological Roles. Cancers (Basel). 2020 Jun 5;12(6):1480. doi: 10.3390/cancers12061480. PMID: 32517087; PMCID: PMC7352664.
La Manna F, De Menna M, Patel N, Karkampouna S, De Filippo MR, Klima I, Kloen P, Beimers L, Thalmann GN, Pelger RCM, Jacinto E, Kruithof-de Julio M. Dual-mTOR Inhibitor Rapalink-1 Reduces Prostate Cancer Patient-Derived Xenograft Growth and Alters Tumor Heterogeneity. Front Oncol. 2020 Jun 23;10:1012. doi: 10.3389/fonc.2020.01012. PMID: 32656088; PMCID: PMC7324765.
Kruithof-de Julio M, De Menna M. Genitourinary cancer treatment made personal. Innovation Newsnetwork. 2020 May.
Karkampouna S, La Manna F, Benjak A, Kiener M, De Menna M, Zoni E, Grosjean J, Klima I, Garofoli A, Bolis M, Vallerga A, Theurillat JP, De Filippo MR, Genitsch V, Keller D, Booij TH, Stirnimann CU, Eng K, Sboner A, Ng CKY, Piscuoglio S, Gray PC, Spahn M, Rubin MA, Thalmann GN, Kruithof-de Julio M. Patient-derived xenografts and organoids model therapy response in prostate cancer. Nat Commun. 2021 Feb 18;12(1):1117. doi: 10.1038/s41467-021-21300-6. PMID: 33602919; PMCID: PMC7892572.
Karkampouna S, De Filippo MR, Ng CKY, Klima I, Zoni E, Spahn M, Stein F, Haberkant P, Thalmann GN, Kruithof-de Julio M. Stroma Transcriptomic and Proteomic Profile of Prostate Cancer Metastasis Xenograft Models Reveals Prognostic Value of Stroma Signatures. Cancers (Basel). 2020 Dec 15;12(12):3786. doi: 10.3390/cancers12123786. PMID: 33334054; PMCID: PMC7768471.
Zoni E, Minoli M, Bovet C, Wehrhan A, Piscuoglio S, Ng CKY, Gray PC, Spahn M, Thalmann GN, Kruithof-de Julio M. Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification. BMC Cancer. 2019 Dec 16;19(1):1216. doi: 10.1186/s12885-019-6418-2. PMID: 31842810; PMCID: PMC6916032.
Krebs M, Behrmann C, Kalogirou C, Sokolakis I, Kneitz S, Kruithof-de Julio M, Zoni E, Rech A, Schilling B, Kübler H, Spahn M, Kneitz B. miR-221 Augments TRAIL-Mediated Apoptosis in Prostate Cancer Cells by Inducing Endogenous TRAIL Expression and Targeting the Functional Repressors SOCS3 and PIK3R1. Biomed Res Int. 2019 Nov 14;2019:6392748. doi: 10.1155/2019/6392748. PMID: 31828111; PMCID: PMC6881584.
Chen L, De Menna M, Groenewoud A, Thalmann GN, Kruithof-de Julio M, Snaar-Jagalska BE. A NF-ĸB-Activin A signaling axis enhances prostate cancer metastasis. Oncogene. 2020 Feb;39(8):1634-1651. doi: 10.1038/s41388-019-1103-0. Epub 2019 Nov 18. PMID: 31740783.
Genitsch V, Kollár A, Vandekerkhove G, Blarer J, Furrer M, Annala M, Herberts C, Pycha A, de Jong JJ, Liu Y, Krentel F, Davicioni E, Gibb EA, Kruithof-de Julio M, Wyatt AW, Seiler R. Morphologic and genomic characterization of urothelial to sarcomatoid transition in muscle-invasive bladder cancer. Urol Oncol. 2019 Nov;37(11):826-836. doi: 10.1016/j.urolonc.2019.09.025. Epub 2019 Oct 1. PMID: 31585777.
Kiener M, Chen L, Krebs M, Grosjean J, Klima I, Kalogirou C, Riedmiller H, Kneitz B, Thalmann GN, Snaar-Jagalska E, Spahn M, Kruithof-de Julio M, Zoni E. miR-221-5p regulates proliferation and migration in human prostate cancer cells and reduces tumor growth in vivo. BMC Cancer. 2019 Jun 25;19(1):627. doi: 10.1186/s12885-019-5819-6. PMID: 31238903; PMCID: PMC6593572.
Zoni E, Astrologo L, Ng CKY, Piscuoglio S, Melsen J, Grosjean J, Klima I, Chen L, Snaar-Jagalska EB, Flanagan K, van der Pluijm G, Kloen P, Cecchini MG, Kruithof-de Julio M, Thalmann GN. Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer. Mol Cancer Res. 2019 May;17(5):1049-1062. doi: 10.1158/1541-7786.MCR-18-1220. Epub 2019 Feb 11. PMID: 30745464.
Tulotta C, Lefley DV, Freeman K, Gregory WM, Hanby AM, Heath PR, Nutter F, Wilkinson JM, Spicer-Hadlington AR, Liu X, Bradbury SMJ, Hambley L, Cookson V, Allocca G, Kruithof de Julio M, Coleman RE, Brown JE, Holen I, Ottewell PD. Endogenous Production of IL1B by Breast Cancer Cells Drives Metastasis and Colonization of the Bone Microenvironment. Clin Cancer Res. 2019 May 1;25(9):2769-2782. doi: 10.1158/1078-0432.CCR-18-2202. Epub 2019 Jan 22. PMID: 30670488.
La Manna F, Karkampouna S, Zoni E, De Menna M, Hensel J, Thalmann GN, Kruithof-de Julio M. Erratum: Metastases in Prostate Cancer. Cold Spring Harb Perspect Med. 2018 Jul 2;8(7):a035568. doi: 10.1101/cshperspect.a035568. Erratum for: Cold Spring Harb Perspect Med. 2018 Jun 14;: PMID: 29967098; PMCID: PMC6027929.
Karkampouna S, van der Helm D, Gray PC, Chen L, Klima I, Grosjean J, Burgmans MC, Farina-Sarasqueta A, Snaar-Jagalska EB, Stroka DM, Terracciano L, van Hoek B, Schaapherder AF, Osanto S, Thalmann GN, Verspaget HW, Coenraad MJ, Kruithof-de Julio M. CRIPTO promotes an aggressive tumour phenotype and resistance to treatment in hepatocellular carcinoma. J Pathol. 2018 Jul;245(3):297-310. doi: 10.1002/path.5083. Epub 2018 May 9. PMID: 29604056.
Kappel S, Marques IJ, Zoni E, Stokłosa P, Peinelt C, Mercader N, Kruithof-de Julio M, Borgström A. Correction to: Store-Operated Ca2+ Entry as a Prostate Cancer Biomarker - a Riddle with Perspectives. Curr Mol Biol Rep. 2018;4(3):142. doi: 10.1007/s40610-018-0097-7. Epub 2018 Jun 20. Erratum for: Curr Mol Biol Rep. 2017;3(4):208-217. PMID: 31187023; PMCID: PMC6096868.
Astrologo L, Zoni E, Karkampouna S, Gray PC, Klima I, Grosjean J, Goumans MJ, Hawinkels LJAC, van der Pluijm G, Spahn M, Thalmann GN, Ten Dijke P, Kruithof-de Julio M. ALK1Fc Suppresses the Human Prostate Cancer Growth in in Vitro and in Vivo Preclinical Models. Front Cell Dev Biol. 2017 Dec 5;5:104. doi: 10.3389/fcell.2017.00104. PMID: 29259971; PMCID: PMC5723291.
Zoni E, Chen L, Karkampouna S, Granchi Z, Verhoef EI, La Manna F, Kelber J, Pelger RCM, Henry MD, Snaar-Jagalska E, van Leenders GJLH, Beimers L, Kloen P, Gray PC, van der Pluijm G, Kruithof-de Julio M. CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer. Oncogene. 2017 Aug 17;36(33):4739-4749. doi: 10.1038/onc.2017.87. Epub 2017 Apr 10. PMID: 28394345; PMCID: PMC5562855.
Zoni E, Karkampouna S, Thalmann GN, Kruithof-de Julio M, Spahn M. Emerging aspects of microRNA interaction with TMPRSS2-ERG and endocrine therapy. Mol Cell Endocrinol. 2018 Feb 15;462(Pt A):9-16. doi: 10.1016/j.mce.2017.02.009. Epub 2017 Feb 9. PMID: 28189568.
Chen L, Groenewoud A, Tulotta C, Zoni E, Kruithof-de Julio M, van der Horst G, van der Pluijm G, Ewa Snaar-Jagalska B. A zebrafish xenograft model for studying human cancer stem cells in distant metastasis and therapy response. Methods Cell Biol. 2017;138:471-496. doi: 10.1016/bs.mcb.2016.10.009. Epub 2016 Dec 9. PMID: 28129855.
Kappel S, Marques IJ, Zoni E, Stokłosa P, Peinelt C, Mercader N, Kruithof-de Julio M, Borgström A. Store-Operated Ca2+ Entry as a Prostate Cancer Biomarker - a Riddle with Perspectives. Curr Mol Biol Rep. 2017;3(4):208-217. doi: 10.1007/s40610-017-0072-8. Epub 2017 Oct 28. Erratum in: Curr Mol Biol Rep. 2018;4(3):142. PMID: 29951353; PMCID: PMC6010502.
Karkampouna S, Kreulen M, Obdeijn MC, Kloen P, Dorjée AL, Rivellese F, Chojnowski A, Clark I, Kruithof-de Julio M. Connective Tissue Degeneration: Mechanisms of Palmar Fascia Degeneration (Dupuytren's Disease). Curr Mol Biol Rep. 2016;2(3):133-140. doi: 10.1007/s40610-016-0045-3. Epub 2016 Jul 14. PMID: 27617187; PMCID: PMC4996878.
Dai J, Hensel J, Wang N, Kruithof-de Julio M, Shiozawa Y. Mouse models for studying prostate cancer bone metastasis. Bonekey Rep. 2016 Feb 17;5:777. doi: 10.1038/bonekey.2016.4. PMID: 26916039; PMCID: PMC4757481.
Hawinkels LJ, de Vinuesa AG, Paauwe M, Kruithof-de Julio M, Wiercinska E, Pardali E, Mezzanotte L, Keereweer S, Braumuller TM, Heijkants RC, Jonkers J, Löwik CW, Goumans MJ, ten Hagen TL, ten Dijke P. Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors. Clin Cancer Res. 2016 Jan 1;22(1):96-106. doi: 10.1158/1078-0432.CCR-15-0743. Epub 2015 Sep 15. PMID: 26373572.
Karkampouna S, Goumans MJ, Ten Dijke P, Dooley S, Kruithof-de Julio M. Inhibition of TGFβ type I receptor activity facilitates liver regeneration upon acute CCl4 intoxication in mice. Arch Toxicol. 2016 Feb;90(2):347-57. doi: 10.1007/s00204-014-1436-y. Epub 2015 Jan 8. PMID: 25566828.
