2022
Wegner, F. et al. External Quality Assessment of SARS-CoV-2 Sequencing: an ESGMD-SSM Pilot Trial across 15 European Laboratories. J Clin Microbiol 60, e0169821, doi:10.1128/jcm.01698-21 (2022).
Wegner F, Roloff T, Huber M, Cordey S, Ramette A, Gerth Y, Bertelli C, Stange M, Seth-Smith HMB, Mari A, Leuzinger K, Cerutti L, Harshman K, Xenarios I, Le Mercier P, Bittel P, Neuenschwander S, Opota O, Fuchs J, Panning M, Michel C, Hallin M, Demuyser T, De Mendonca R, Savelkoul P, Dingemans J, van der Veer B, Boers SA, Claas ECJ, Coolen JPM, Melchers WJG, Gunell M, Kallonen T, Vuorinen T, Hakanen AJ, Bernhoff E, Hetland MAK, Golan Berman H, Adar S, Moran-Gilad J, Wolf DG, Leib SL, Nolte O, Kaiser L, Schmutz S, Kufner V, Zaheri M, Trkola A, Aamot HV, Hirsch HH, Greub G, Egli A. External Quality Assessment of SARS-CoV-2 Sequencing: an ESGMD-SSM Pilot Trial across 15 European Laboratories. J Clin Microbiol. 2022 Jan 19;60(1):e0169821. doi: 10.1128/JCM.01698-21. Epub 2021 Nov 10. PMID: 34757834; PMCID: PMC8769736.
2021
Engelter ST, Traenka C, Gensicke H, Schaedelin SA, Luft AR, Simonetti BG, Fischer U, Michel P, Sirimarco G, Kägi G, Vehoff J, Nedeltchev K, Kahles T, Kellert L, Rosenbaum S, von Rennenberg R, Sztajzel R, Leib SL, Jung S, Gralla J, Bruni N, Seiffge D, Feil K, Polymeris AA, Steiner L, Hamann J, Bonati LH, Brehm A, De Marchis GM, Peters N, Stippich C, Nolte CH, Christensen H, Wegener S, Psychogios MN, Arnold M, Lyrer P; TREAT-CAD investigators. Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial. Lancet Neurol. 2021 May;20(5):341-350. doi: 10.1016/S1474-4422(21)00044-2. Epub 2021 Mar 23. PMID: 33765420.
Ungureanu A, van der Meer J, Bicvic A, Abbuehl L, Chiffi G, Jaques L, Suter-Riniker F, Leib SL, Bassetti CLA, Dietmann A. Meningitis, meningoencephalitis and encephalitis in Bern: an observational study of 258 patients. BMC Neurol. 2021 Dec 6;21(1):474. doi: 10.1186/s12883-021-02502-3. PMID: 34872509; PMCID: PMC8647376.
Jebbawi F, Bellanger AP, Lunström-Stadelmann B, Rufener R, Dosch M, Goepfert C, Gottstein B, Millon L, Grandgirard D, Leib SL, Beldi G, Wang J. Innate and adaptive immune responses following PD-L1 blockade in treating chronic murine alveolar echinococcosis. Parasite Immunol. 2021 Aug;43(8):e12834. doi: 10.1111/pim.12834. Epub 2021 May 7. PMID: 33754355.
Wegner F, Roloff T, Huber M, Cordey S, Ramette A, Gerth Y, Bertelli C, Stange M, Seth-Smith HMB, Mari A, Leuzinger K, Cerutti L, Harshman K, Xenarios I, Le Mercier P, Bittel P, Neuenschwander S, Opota O, Fuchs J, Panning M, Michel C, Hallin M, Demuyser T, De Mendonca R, Savelkoul P, Dingemans J, van der Veer B, Boers SA, Claas ECJ, Coolen JPM, Melchers WJG, Gunell M, Kallonen T, Vuorinen T, Hakanen AJ, Bernhoff E, Hetland MAK, Golan Berman H, Adar S, Moran-Gilad J, Wolf DG, Leib SL, Nolte O, Kaiser L, Schmutz S, Kufner V, Zaheri M, Trkola A, Aamot HV, Hirsch HH, Greub G, Egli A. External Quality Assessment of SARS-CoV-2 Sequencing: an ESGMD-SSM Pilot Trial across 15 European Laboratories. J Clin Microbiol. 2022 Jan 19;60(1):e0169821. doi: 10.1128/JCM.01698-21. Epub 2021 Nov 10. PMID: 34757834; PMCID: PMC8769736.
Erni ST, Gill JC, Palaferri C, Fernandes G, Buri M, Lazarides K, Grandgirard D, Edge ASB, Leib SL, Roccio M. Hair Cell Generation in Cochlear Culture Models Mediated by Novel γ-Secretase Inhibitors. Front Cell Dev Biol. 2021 Aug 13;9:710159. doi: 10.3389/fcell.2021.710159. PMID: 34485296; PMCID: PMC8414802.
Grüter BE, Wanderer S, Strange F, Boillat G, Täschler D, Rey J, Croci DM, Grandgirard D, Leib SL, von Gunten M, Di Santo S, Widmer HR, Remonda L, Andereggen L, Nevzati E, Coluccia D, Fandino J, Marbacher S. Patterns of Neointima Formation After Coil or Stent Treatment in a Rat Saccular Sidewall Aneurysm Model. Stroke. 2021 Mar;52(3):1043-1052. doi: 10.1161/STROKEAHA.120.032255. Epub 2021 Jan 28. PMID: 33504186.
Wang J, von Gunten S, Beldi G, Grandgirard D, Leib SL, Gottstein B. Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology. 2021;106(1-2):3-8. doi: 10.1159/000509355. Epub 2020 Jul 31. PMID: 32739918.
Akello JO, Kamgang R, Barbani MT, Suter-Riniker F, Aebi C, Beuret C, Paris DH, Leib SL, Ramette A. Genomic analyses of human adenoviruses unravel novel recombinant genotypes associated with severe infections in pediatric patients. Sci Rep. 2021 Dec 15;11(1):24038. doi: 10.1038/s41598-021-03445-y. PMID: 34912023; PMCID: PMC8674331
Oyewole OR, Lang P, Albrich WC, Wissel K, Leib SL, Casanova C, Hilty M. The Impact of Pneumococcal Conjugate Vaccine (PCV) Coverage Heterogeneities on the Changing Epidemiology of Invasive Pneumococcal Disease in Switzerland, 2005-2019. Microorganisms. 2021 May 18;9(5):1078. doi: 10.3390/microorganisms9051078. PMID: 34069761; PMCID: PMC8157260.
Goncalves Cabecinhas AR, Roloff T, Stange M, Bertelli C, Huber M, Ramette A, Chen C, Nadeau S, Gerth Y, Yerly S, Opota O, Pillonel T, Schuster T, Metzger CMJA, Sieber J, Bel M, Wohlwend N, Baumann C, Koch MC, Bittel P, Leuzinger K, Brunner M, Suter-Riniker F, Berlinger L, Søgaard KK, Beckmann C, Noppen C, Redondo M, Steffen I, Seth-Smith HMB, Mari A, Lienhard R, Risch M, Nolte O, Eckerle I, Martinetti Lucchini G, Hodcroft EB, Neher RA, Stadler T, Hirsch HH, Leib SL, Risch L, Kaiser L, Trkola A, Greub G, Egli A. SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021-Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing. Microorganisms. 2021 Mar 25;9(4):677. doi: 10.3390/microorganisms9040677. PMID: 33806013; PMCID: PMC8064472.
Prazak J, Valente L, Iten M, Federer L, Grandgirard D, Soto S, Resch G, Leib SL, Jakob SM, Haenggi M, Cameron DR, Que YA. Benefits of aerosolized phages for the treatment of pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA): an experimental study in rats. J Infect Dis. 2021 Mar 1:jiab112. doi: 10.1093/infdis/jiab112. Epub ahead of print. PMID: 33668071.
Valente LG, Federer L, Iten M, Grandgirard D, Leib SL, Jakob SM, Haenggi M, Cameron DR, Que YA, Prazak J. Searching for synergy: combining systemic daptomycin treatment with localised phage therapy for the treatment of experimental pneumonia due to MRSA. BMC Res Notes. 2021 Sep 27;14(1):381. doi: 10.1186/s13104-021-05796-1. PMID: 34579784; PMCID: PMC8474762.
Casanova C, Küffer M, Leib SL, Hilty M. Re-emergence of invasive pneumococcal disease (IPD) and increase of serotype 23B after easing of COVID-19 measures, Switzerland, 2021. Emerg Microbes Infect. 2021 Dec;10(1):2202-2204. doi: 10.1080/22221751.2021.2000892. PMID: 34723783; PMCID: PMC8648035.
2020
Brigger D, Riether C, van Brummelen R, Mosher KI, Shiu A, Ding Z, Zbären N, Gasser P, Guntern P, Yousef H, Castellano JM, Storni F, Graff-Radford N, Britschgi M, Grandgirard D, Hinterbrandner M, Siegrist M, Moullan N, Hofstetter W, Leib SL, Villiger PM, Auwerx J, Villeda SA, Wyss-Coray T, Noti M, Eggel A. Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nat Metab. 2020 Aug;2(8):688-702. doi: 10.1038/s42255-020-0228-3. Epub 2020 Jul 6. PMID: 32694825; PMCID: PMC7438316.
Akello JO, Leib SL, Engler O, Beuret C. Evaluation of Viral RNA Recovery Methods in Vectors by Metagenomic Sequencing. Viruses. 2020 May 19;12(5):562. doi: 10.3390/v12050562. PMID: 32438629; PMCID: PMC7290855.
Zbinden FR, De Ste Croix M, Grandgirard D, Haigh RD, Vacca I, Zamudio R, Goodall ECA, Stephan R, Oggioni MR, Leib SL. Pathogenic Differences of Type 1 Restriction-Modification Allele Variants in Experimental Listeria monocytogenes Meningitis. Front Cell Infect Microbiol. 2020 Oct 30;10:590657. doi: 10.3389/fcimb.2020.590657. PMID: 33194838; PMCID: PMC7662400.
Akello JO, Kamgang R, Barbani MT, Suter-Riniker F, Leib SL, Ramette A. Epidemiology of Human Adenoviruses: A 20-Year Retrospective Observational Study in Hospitalized Patients in Bern, Switzerland. Clin Epidemiol. 2020 Apr 5;12:353-366. doi: 10.2147/CLEP.S246352. PMID: 32308491; PMCID: PMC7147615.
Wasimuddin, Schlaeppi K, Ronchi F, Leib SL, Erb M, Ramette A. Evaluation of primer pairs for microbiome profiling from soils to humans within the One Health framework. Mol Ecol Resour. 2020 Nov;20(6):1558-1571. doi: 10.1111/1755-0998.13215. Epub 2020 Aug 18. PMID: 32599660; PMCID: PMC7693082.
Muri L, Oberhänsli S, Buri M, Le ND, Grandgirard D, Bruggmann R, Müri RM, Leib SL. Repetitive transcranial magnetic stimulation activates glial cells and inhibits neurogenesis after pneumococcal meningitis. PLoS One. 2020 Sep 11;15(9):e0232863. doi: 10.1371/journal.pone.0232863. PMID: 32915781; PMCID: PMC7485822.
Brigger D, Horn MP, Pennington LF, Powell AE, Siegrist D, Weber B, Engler O, Piezzi V, Damonti L, Iseli P, Hauser C, Froehlich TK, Villiger PM, Bachmann MF, Leib SL, Bittel P, Fiedler M, Largiadèr CR, Marschall J, Stalder H, Kim PS, Jardetzky TS, Eggel A, Nagler M. Accuracy of serological testing for SARS-CoV-2 antibodies: First results of a large mixed-method evaluation study. Allergy. 2021 Mar;76(3):853-865. doi: 10.1111/all.14608. Epub 2020 Nov 13. PMID: 32997812; PMCID: PMC7537154.
gli A, Battegay M, Büchler AC, Bühlmann P, Calandra T, Eckert P, Furrer H, Greub G, Jakob SM, Kaiser L, Leib SL, Marsch S, Meinshausen N, Pagani JL, Pugin J, Rätsch G, Schrenzel J, Schüpbach R, Siegemund M, Zamboni N, Zbinden R, Zinkernagel A, Borgwardt K. SPHN/PHRT: Forming a Swiss-Wide Infrastructure for Data-Driven Sepsis Research. Stud Health Technol Inform. 2020 Jun 16;270:1163-1167. doi: 10.3233/SHTI200346. PMID: 32570564.
Le ND, Muri L, Grandgirard D, Kuhle J, Leppert D, Leib SL. Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis. J Neuroinflammation. 2020 Oct 7;17(1):293. doi: 10.1186/s12974-020-01966-3. PMID: 33028339; PMCID: PMC7539528.
Neuenschwander SM, Terrazos Miani MA, Amlang H, Perroulaz C, Bittel P, Casanova C, Droz S, Flandrois JP, Leib SL, Suter-Riniker F, Ramette A. A Sample-to-Report Solution for Taxonomic Identification of Cultured Bacteria in the Clinical Setting Based on Nanopore Sequencing. J Clin Microbiol. 2020 May 26;58(6):e00060-20. doi: 10.1128/JCM.00060-20. PMID: 32229603; PMCID: PMC7269405.
Ricci S, Grandgirard D, Masouris I, Braccini T, Pozzi G, Oggioni MR, Koedel U, Leib SL. Combined therapy with ceftriaxone and doxycycline does not improve the outcome of meningococcal meningitis in mice compared to ceftriaxone monotherapy. BMC Infect Dis. 2020 Jul 13;20(1):505. doi: 10.1186/s12879-020-05226-w. PMID: 32660552; PMCID: PMC7359289.
Prazak J, Valente L, Iten M, Grandgirard D, Leib SL, Jakob SM, Haenggi M, Que YA, Cameron DR. Nebulized Bacteriophages for Prophylaxis of Experimental Ventilator-Associated Pneumonia Due to Methicillin-Resistant Staphylococcus aureus. Crit Care Med. 2020 Jul;48(7):1042-1046. doi: 10.1097/CCM.0000000000004352. PMID: 32304419.
Pan SD, Grandgirard D, Leib SL. Adjuvant Cannabinoid Receptor Type 2 Agonist Modulates the Polarization of Microglia Towards a Non-Inflammatory Phenotype in Experimental Pneumococcal Meningitis. Front Cell Infect Microbiol. 2020 Nov 5;10:588195. doi: 10.3389/fcimb.2020.588195. PMID: 33251159; PMCID: PMC7674855.
Grädel C, Terrazos Miani MA, Baumann C, Barbani MT, Neuenschwander S, Leib SL, Suter-Riniker F, Ramette A. Whole-Genome Sequencing of Human Enteroviruses from Clinical Samples by Nanopore Direct RNA Sequencing. Viruses. 2020 Jul 31;12(8):841. doi: 10.3390/v12080841. PMID: 32752120; PMCID: PMC7472277.
Meyer P, Grandgirard D, Lehner M, Haenggi M, Leib SL. Grafted Neural Progenitor Cells Persist in the Injured Site and Differentiate Neuronally in a Rodent Model of Cardiac Arrest-Induced Global Brain Ischemia. Stem Cells Dev. 2020 May 1;29(9):574-585. doi: 10.1089/scd.2019.0190. Epub 2020 Feb 19. PMID: 31964231.
2019
Muri L, Leppert D, Grandgirard D, Leib SL. MMPs and ADAMs in neurological infectious diseases and multiple sclerosis. Cell Mol Life Sci. 2019 Aug;76(16):3097-3116. doi: 10.1007/s00018-019-03174-6. Epub 2019 Jun 6. PMID: 31172218; PMCID: PMC7079810.
Ott SR, Meier N, Kolditz M, Bauer TT, Rohde G, Presterl E, Schürmann D, Lepper PM, Ringshausen FC, Flick H, Leib SL, Pletz MW; OPINION Study Group. Pulmonary nocardiosis in Western Europe-Clinical evaluation of 43 patients and population-based estimates of hospitalization rates. Int J Infect Dis. 2019 Apr;81:140-148. doi: 10.1016/j.ijid.2018.12.010. Epub 2019 Jan 15. PMID: 30658169.
Grüter BE, Täschler D, Strange F, Rey J, von Gunten M, Grandgirard D, Leib SL, Remonda L, Widmer HR, Nevzati E, Fandino J, Marbacher S, Coluccia D. Testing bioresorbable stent feasibility in a rat aneurysm model. J Neurointerv Surg. 2019 Oct;11(10):1050-1054. doi: 10.1136/neurintsurg-2018-014697. Epub 2019 Mar 9. PMID: 30852526.
Muri L, Le ND, Zemp J, Grandgirard D, Leib SL. Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis. J Neuroinflammation. 2019 Jul 27;16(1):156. doi: 10.1186/s12974-019-1549-6. PMID: 31351490; PMCID: PMC6660697.
Prazak J, Iten M, Cameron DR, Save J, Grandgirard D, Resch G, Goepfert C, Leib SL, Takala J, Jakob SM, Que YA, Haenggi M. Bacteriophages Improve Outcomes in Experimental Staphylococcus aureus Ventilator-associated Pneumonia. Am J Respir Crit Care Med. 2019 Nov 1;200(9):1126-1133. doi: 10.1164/rccm.201812-2372OC. PMID: 31260638.
Grädel C, Terrazos Miani MA, Barbani MT, Leib SL, Suter-Riniker F, Ramette A. Rapid and Cost-Efficient Enterovirus Genotyping from Clinical Samples Using Flongle Flow Cells. Genes (Basel). 2019 Aug 29;10(9):659. doi: 10.3390/genes10090659. PMID: 31470607; PMCID: PMC6770998.
Hupp S, Grandgirard D, Mitchell TJ, Leib SL, Hathaway LJ, Iliev AI. Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia. J Neuroinflammation. 2019 May 18;16(1):105. doi: 10.1186/s12974-019-1491-7. PMID: 31103037; PMCID: PMC6525981.
Ackermann-Gäumann R, Eyer C, Leib SL, Niederhauser C. Comparison of Four Commercial IgG-Enzyme-Linked Immunosorbent Assays for the Detection of Tick-Borne Encephalitis Virus Antibodies. Vector Borne Zoonotic Dis. 2019 May;19(5):358-364. doi: 10.1089/vbz.2018.2359. Epub 2018 Dec 4. PMID: 30523740.E
Erni ST, Fernandes G, Buri M, Perny M, Rutten RJ, van Noort JM, Senn P, Grandgirard D, Roccio M, Leib SL. Anti-inflammatory and Oto-Protective Effect of the Small Heat Shock Protein Alpha B-Crystallin (HspB5) in Experimental Pneumococcal Meningitis. Front Neurol. 2019 Jun 10;10:570. doi: 10.3389/fneur.2019.00570. PMID: 31244750; PMCID: PMC6573805.
Muri L, Perny M, Zemp J, Grandgirard D, Leib SL. Combining Ceftriaxone with Doxycycline and Daptomycin Reduces Mortality, Neuroinflammation, Brain Damage, and Hearing Loss in Infant Rat Pneumococcal Meningitis. Antimicrob Agents Chemother. 2019 Jun 24;63(7):e00220-19. doi: 10.1128/AAC.00220-19. PMID: 31061158; PMCID: PMC6591596.
Colicchio R, Pagliuca C, Ricci S, Scaglione E, Grandgirard D, Masouris I, Farina F, Pagliarulo C, Mantova G, Paragliola L, Leib SL, Koedel U, Pozzi G, Alifano P, Salvatore P. Virulence Traits of a Serogroup C Meningococcus and Isogenic cssA Mutant, Defective in Surface-Exposed Sialic Acid, in a Murine Model of Meningitis. Infect Immun. 2019 Mar 25;87(4):e00688-18. doi: 10.1128/IAI.00688-18. PMID: 30718288; PMCID: PMC6434112.
Needle DB, Selig MK, Jackson KA, Delwart E, Tighe E, Leib SL, Seuberlich T, Pesavento PA. Fatal bronchopneumonia caused by skunk adenovirus 1 in an African pygmy hedgehog. J Vet Diagn Invest. 2019 Jan;31(1):103-106. doi: 10.1177/1040638718812123. Epub 2018 Nov 26. PMID: 30475680; PMCID: PMC6505768.
Rosser C, Sager F, Leib SL. Six Recommendations to Build Legitimacy for Translational Research Organizations. Front Med (Lausanne). 2020 Dec 8;7:586177. doi: 10.3389/fmed.2020.586177. PMID: 33364246; PMCID: PMC7755134.
2021
Valente, L. G. et al. Searching for synergy: combining systemic daptomycin treatment with localised phage therapy for the treatment of experimental pneumonia due to MRSA. BMC Res Notes 14, 381, doi:10.1186/s13104-021-05796-1 (2021).
Ungureanu, A. et al. Meningitis, meningoencephalitis and encephalitis in Bern: an observational study of 258 patients. BMC Neurol 21, 474, doi:10.1186/s12883-021-02502-3 (2021).
Prazak, J. et al. Benefits of aerosolized phages for the treatment of pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA): an experimental study in rats. J Infect Dis, doi:10.1093/infdis/jiab112 (2021).
Oyewole, O. R. et al. The Impact of Pneumococcal Conjugate Vaccine (PCV) Coverage Heterogeneities on the Changing Epidemiology of Invasive Pneumococcal Disease in Switzerland, 2005-2019. Microorganisms 9, doi:10.3390/microorganisms9051078 (2021).
Jebbawi, F. et al. Innate and adaptive immune responses following PD-L1 blockade in treating chronic murine alveolar echinococcosis. Parasite Immunol 43, e12834, doi:10.1111/pim.12834 (2021).
Grüter, B. E. et al. Patterns of Neointima Formation After Coil or Stent Treatment in a Rat Saccular Sidewall Aneurysm Model. Stroke 52, 1043-1052, doi:10.1161/strokeaha.120.032255 (2021).
Goncalves Cabecinhas, A. R. et al. SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021-Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing. Microorganisms 9, doi:10.3390/microorganisms9040677 (2021).
Erni, S. T. et al. Hair Cell Generation in Cochlear Culture Models Mediated by Novel γ-Secretase Inhibitors. Front Cell Dev Biol 9, 710159, doi:10.3389/fcell.2021.710159 (2021).
Engelter, S. T. et al. Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial. Lancet Neurol 20, 341-350, doi:10.1016/s1474-4422(21)00044-2 (2021).
Casanova, C., Küffer, M., Leib, S. L. & Hilty, M. Re-emergence of invasive pneumococcal disease (IPD) and increase of serotype 23B after easing of COVID-19 measures, Switzerland, 2021. Emerg Microbes Infect 10, 2202-2204, doi:10.1080/22221751.2021.2000892 (2021).
Brigger, D. et al. Accuracy of serological testing for SARS-CoV-2 antibodies: First results of a large mixed-method evaluation study. Allergy 76, 853-865, doi:10.1111/all.14608 (2021).
Akello, J. O. et al. Genomic analyses of human adenoviruses unravel novel recombinant genotypes associated with severe infections in pediatric patients. Sci Rep 11, 24038, doi:10.1038/s41598-021-03445-y (2021).
2020
Zbinden, F. R. et al. Pathogenic Differences of Type 1 Restriction-Modification Allele Variants in Experimental Listeria monocytogenes Meningitis. Front Cell Infect Microbiol 10, 590657, doi:10.3389/fcimb.2020.590657 (2020).
Wasimuddin et al. Evaluation of primer pairs for microbiome profiling from soils to humans within the One Health framework. Mol Ecol Resour 20, 1558-1571, doi:10.1111/1755-0998.13215 (2020).
Rosser, C., Sager, F. & Leib, S. L. Six Recommendations to Build Legitimacy for Translational Research Organizations. Front Med (Lausanne) 7, 586177, doi:10.3389/fmed.2020.586177 (2020).
Ricci, S. et al. Combined therapy with ceftriaxone and doxycycline does not improve the outcome of meningococcal meningitis in mice compared to ceftriaxone monotherapy. BMC Infect Dis 20, 505, doi:10.1186/s12879-020-05226-w (2020).
Prazak, J. et al. Nebulized Bacteriophages for Prophylaxis of Experimental Ventilator-Associated Pneumonia Due to Methicillin-Resistant Staphylococcus aureus. Crit Care Med 48, 1042-1046, doi:10.1097/ccm.0000000000004352 (2020).
Pan, S. D., Grandgirard, D. & Leib, S. L. Adjuvant Cannabinoid Receptor Type 2 Agonist Modulates the Polarization of Microglia Towards a Non-Inflammatory Phenotype in Experimental Pneumococcal Meningitis. Front Cell Infect Microbiol 10, 588195, doi:10.3389/fcimb.2020.588195 (2020).
Neuenschwander, S. M. et al. A Sample-to-Report Solution for Taxonomic Identification of Cultured Bacteria in the Clinical Setting Based on Nanopore Sequencing. J Clin Microbiol 58, doi:10.1128/jcm.00060-20 (2020).
Muri, L. et al. Repetitive transcranial magnetic stimulation activates glial cells and inhibits neurogenesis after pneumococcal meningitis. PLoS One 15, e0232863, doi:10.1371/journal.pone.0232863 (2020).
Meyer, P., Grandgirard, D., Lehner, M., Haenggi, M. & Leib, S. L. Grafted Neural Progenitor Cells Persist in the Injured Site and Differentiate Neuronally in a Rodent Model of Cardiac Arrest-Induced Global Brain Ischemia. Stem Cells Dev 29, 574-585, doi:10.1089/scd.2019.0190 (2020).
Le, N. D. et al. Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis. J Neuroinflammation 17, 293, doi:10.1186/s12974-020-01966-3 (2020).
Grädel, C. et al. Whole-Genome Sequencing of Human Enteroviruses from Clinical Samples by Nanopore Direct RNA Sequencing. Viruses 12, doi:10.3390/v12080841 (2020).
Egli, A. et al. SPHN/PHRT: Forming a Swiss-Wide Infrastructure for Data-Driven Sepsis Research. Stud Health Technol Inform 270, 1163-1167, doi:10.3233/shti200346 (2020).
Brigger, D. et al. Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nat Metab 2, 688-702, doi:10.1038/s42255-020-0228-3 (2020).
Akello, J. O., Leib, S. L., Engler, O. & Beuret, C. Evaluation of Viral RNA Recovery Methods in Vectors by Metagenomic Sequencing. Viruses 12, doi:10.3390/v12050562 (2020).
Akello, J. O. et al. Epidemiology of Human Adenoviruses: A 20-Year Retrospective Observational Study in Hospitalized Patients in Bern, Switzerland. Clin Epidemiol 12, 353-366, doi:10.2147/clep.S246352 (2020).
2019
Prazak, J. et al. Bacteriophages Improve Outcomes in Experimental Staphylococcus aureus Ventilator-associated Pneumonia. Am J Respir Crit Care Med 200, 1126-1133, doi:10.1164/rccm.201812-2372OC (2019).
Ott, S. R. et al. Pulmonary nocardiosis in Western Europe-Clinical evaluation of 43 patients and population-based estimates of hospitalization rates. Int J Infect Dis 81, 140-148, doi:10.1016/j.ijid.2018.12.010 (2019).
Needle, D. B. et al. Fatal bronchopneumonia caused by skunk adenovirus 1 in an African pygmy hedgehog. J Vet Diagn Invest 31, 103-106, doi:10.1177/1040638718812123 (2019).
Muri, L., Perny, M., Zemp, J., Grandgirard, D. & Leib, S. L. Combining Ceftriaxone with Doxycycline and Daptomycin Reduces Mortality, Neuroinflammation, Brain Damage, and Hearing Loss in Infant Rat Pneumococcal Meningitis. Antimicrob Agents Chemother 63, doi:10.1128/aac.00220-19 (2019).
Muri, L., Leppert, D., Grandgirard, D. & Leib, S. L. MMPs and ADAMs in neurological infectious diseases and multiple sclerosis. Cell Mol Life Sci 76, 3097-3116, doi:10.1007/s00018-019-03174-6 (2019).
Muri, L., Le, N. D., Zemp, J., Grandgirard, D. & Leib, S. L. Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis. J Neuroinflammation 16, 156, doi:10.1186/s12974-019-1549-6 (2019).
Hupp, S. et al. Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia. J Neuroinflammation 16, 105, doi:10.1186/s12974-019-1491-7 (2019).
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