Flück, CE, Rojas Velazquez, MN and Pandey, AV. P450 oxidoreductase deficiency. In Genetic Steroid Disorders 2nd Edition. Ed: Maria I New. 125-143 Elsevier (2023).DOI: https://doi.org/ 10.1016/B978-0-12-821424-4.00012-5
Biason-Lauber, A, Pandey AV, Miller WL, Flück, CE. Steroidogenesis across species: aldo keto reductases in marsupials, fish and humans. . In Genetic Steroid Disorders 2nd Edition. Ed: Maria I New. Elsevier (2023). https://doi.org/10.1016/B978-0-12-821424-4.00002-2
Lucas C, Sauter KS, Steigert M, Mallet D, Wilmouth J, Olabe J, Plotton, I, Morel Y, Aeberli D, Wagner F, Clevers H, Pandey AV, Val P, Roucher Boulez F, Fluck CE. Loss of LGR4/GPR48 causes severe neonatal salt-wasting due to disrupted WNT signaling altering adrenal zonation. J Clin Investigation 2023 Feb 15;133(4):e164915. doi: 10.1172/JCI164915. PMID: 36538378
Grassi M, Laubscher B, Pandey A, V, Tschumi S, Graber F, Schaller A, Janner M, Aeberli D, Hewer E, Nuoffer J, -M, Gautschi M: Expanding the p.(Arg85Trp) Variant-Specific Phenotype of HNF4A: Features of Glycogen Storage Disease, Liver Cirrhosis, Impaired Mitochondrial Function, and Glomerular Changes. Mol Syndromol 2023. doi: 10.1159/000529306
Wróbel TM, ,Jørgensen FS, Pandey AV, Grudzińska A, Sharma K, Yakubu J and Björkling F. Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment. J. Med. Chem. 2023 (In press)
Rojas Velazquez MN, Noebauer M, Pandey AV. Loss of Protein Stability and Function Caused by P228L Variation in NADPH-Cytochrome P450 Reductase Linked to Lower Testosterone Levels. Int J Mol Sci. 2022 Sep 4;23(17):10141. doi: 10.3390/ijms231710141. PMID: 36077536
Prado MJ, Ligabue-Braun R, Zaha A, Rossetti MLR, Pandey AV. Variant predictions in congenital adrenal hyperplasia caused by mutations in CYP21A2. Front Pharmacol. 2022 Oct 5;13:931089. doi: 10.3389/fphar.2022.931089. PMID: 36278220
Verma S, Chakraborti S, Singh OP, Pande V, Dixit R, Pandey AV, Pandey KC. Recognition of fold- and function-specific sites in the ligand-binding domain of the thyroid hormone receptor-like family. Front Endocrinol. 2022 Sep 29;13:981090. doi: 10.3389/fendo.2022.981090. PMID: 36246927
Wróbel TM, Rogova O, Sharma K, Rojas Velazquez MN, Pandey AV, Jørgensen FS, Arendrup FS, Andersen KL, Björkling F. Synthesis and Structure-Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents. Biomolecules. 2022 Jan 20;12(2):165. doi: 10.3390/biom12020165. PMID: 35204665
Prado MJ, Singh S, Ligabue-Braun R, Meneghetti BV, Rispoli T, Kopacek C, Monteiro K, Zaha A, Rossetti MLR, Pandey AV. Characterization of Mutations Causing CYP21A2 Deficiency in Brazilian and Portuguese Populations. Int J Mol Sci. 2022 Dec 28;23(1):296. doi: 10.3390/ijms23010296. PMID: 35008721
Simon B Jensen, Sara Thodberg, Shaheena Parween, Matias E. Moses, Cecilie T Hansen, Johannes Thomsen, Magnus B. Sletfjerding, Camilla Knudsen, Rita Giudice, Philip Lund, Patricia Castano, Yanet Bustamante, Maria Natalia Velasquez, Flemming S Jørgensen, Amit V. Pandey, Tomas Laursen, Birger L Møller, Nikos Hatzakis. Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase. Nature Communications 2021 Apr 15;12(1):2260. doi: 10.1038/s41467-021-22562-w.PMID: 33859207
Humbert M, Seiler K, Mosimann S, Rentsch V, Sharma K, Pandey AV, McKenna SL, Tschan MP. Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy. Cell Death Differ. 2021 Mar 19. doi: 10.1038/s41418-021-00768-1. PMID: 33742137.
Parween S, Fernández-Cancio M, Benito-Sanz S, Camats N, Rojas Velazquez MN, López-Siguero JP, Udhane SS, Kagawa N, Flück CE, Audí L, Pandey AV. Molecular Basis of CYP19A1 Deficiency in a 46,XX Patient With R550W Mutation in POR:Expanding the PORD Phenotype. J Clin Endocrinol Metab. 2020 Apr 1;105(4). pii:dgaa076. doi: 10.1210/clinem/dgaa076. PMID: 32060549
Flück CE, Parween S, Rojas Velazquez MN and Pandey AV. Inhibition of placental CYP19A1 activity remains as a valid hypothesis for 46,XX virilization in P450 oxidoreductase deficiency. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):14632-14633. doi: 10.1073/pnas.2003154117
An updated list of publications at: Amit V Pandey - Google Scholar
