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Emerging and Difficult to Treat Infections - EDI
Schefold Lab
Team
Ongoing Projects
Publications
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Publications
Current gaps in sepsis immunology: new opportunities for translational research.
Rubio I, Osuchowski MF, Shankar-Hari M, Skirecki T, Winkler MS, Lachmann G, La Rosée P, Monneret G, Venet F, Bauer M, Brunkhorst FM, Kox M, Cavaillon JM, Uhle F, Weigand MA, Flohé SB, Wiersinga WJ, Martin-Fernandez M, Almansa R, Martin-Loeches I, Torres A, Giamarellos-Bourboulis EJ, Girardis M, Cossarizza A, Netea MG, van der Poll T, Scherag A, Meisel C, Schefold JC, Bermejo-Martín JF. Lancet Infect Dis. 2019 Dec; 19(12): e422-e436.
Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.
Meisel C*, Schefold JC*, Pschowski R, Baumann T, Hetzger K, Gregor J, Weber-Carstens S, Hasper D, Keh D, Zuckermann H, Reinke P, Volk HD (* equal contribution). Am J Respir Crit Care Med. 2009 Oct 1;180(7):640-8.
Pantoprazole in patients at risk for gastrointestinal bleeding in the ICU.
Krag M, Marker S, Perner A, Wetterslev J, Wise MP, Schefold JC, Keus F, Guttormsen AB, Bendel S, Borthwick M, Lange T, Rasmussen BS, Siegemund M, Bundgaard H, Elkmann T, Jensen JV, Nielsen RD, Liboriussen L, Bestle MH, Elkjær JM, Palmqvist DF, Bäcklund M, Laake JH, Bådstøløkken PM, Grönlund J, Breum O, Walli A, Winding R, Iversen S, Jarnvig IL, White JO, Brand B, Madsen MB, Quist L, Thornberg KJ, Møller A, Wiis J, Granholm A, Anthon CT, Meyhoff TS, Hjortrup PB, Aagaard SR, Andreasen JB, Sørensen CA, Haure P, Hauge J, Hollinger A, Scheuzger J, Tuchscherer D, Vuilliomenet T, Takala J, Jakob SM, Vang ML, Pælestik KB, Andersen KLD, van der Horst ICC, Dieperink W, Fjølner J, Kjer CKW, Sølling C, Sølling CG, Karttunen J, Morgan MPG, Sjøbø B, Engstrøm J, Agerholm-Larsen B, Møller MH, SUP-ICU trial group. N Engl J Med. 2018 Dec 6;379(23):2199-2208.
Changes in end-of-life practices in European intensive care units from 1999 to 2016.
Sprung CL, Ricou B, Hartog CS, Maia P, Mentzelopoulos SD, Weiss M, Levin PD, Galarza L, de la Guardia V, Schefold JC, Baras M, Joynt GM, Bülow HH, Nakos G, Cerny V, Marsch S, Girbes AR, Ingels C, Miskolci O, Ledoux D, Mullick S, Bocci MG, Gjedsted J, Estébanez B, Nates JL, Lesieur O, Sreedharan R, Giannini AM, Fuciños LC, Danbury CM, Michalsen A, Soliman IW, Estella A, Avidan A. JAMA. 2019 Oct 2;322(17):1-12.
Hypertonic saline for fluid resuscitation in ICU patients post cardiac surgery (HERACLES) – a double-blind randomized controlled clinical trial.
Pfortmueller CA, Kindler M, Schenk N, Messmer AS, Hess B, Jakob L, Wenger S, Waskowski J, Zuercher P, Stoehr F, Jakob SM, Englberger L, Schefold JC. Intensive Care Med. 2020 Sep;46(9):1683-1695.
Dysphagia in mechanically ventilated ICU patients (DYnAMICS): a prospective observational trial.
Schefold JC, Berger D, Zürcher P, Lensch M, Perren A, Jakob SM, Parviainen I, Takala J. Crit Care Med. 2017 Dec;45(12):2061-2069.
Risk factors for dysphagia in ICU patients after invasive mechanical ventilation.
Zuercher P, Schenk NV, Moret C, Berger D, Abegglen R, Schefold JC. Chest. 2020 Nov;158(5):1983-1991.
Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management.
Zuercher P, Moret CS, Dziewas R, Schefold JC. Crit Care. 2019 Mar 28;23(1):103.
Lower or higher oxygenation targets for acute hypoxemic respiratory failure.
Schjørring OL, Klitgaard T, Perner A , Wetterslev J, Lange T , Siegemund M, Bäcklund M, Keus F, Laake JH, Morgan M, Thormar KM, Rosborg SA, Bisgaard J, Erntgaard AES, Lynnerup ASH, Pedersen RL, Crescioli E, Gielstrup TC, Behzadi MT, Poulsen LM, Estrup S , Laigaard JP , Andersen C, Mortensen CB, Brand BA, White J, Jarnvig IL, Møller MH, Quist L, Bestle MH, Schønemann-Lund M, Kamper MK, Hindborg M, Hollinger A, Gebhard CE, Zellweger N, Meyhoff CS, Hjort M, Bech LK, Grøfte T, Bundgaard H, Østergaard LHM, Thyø MA, Hildebrandt T, Uslu B, Sølling CG, Møller-Nielsen N, Brøchner AC, Borup M, Okkonen M, Dieperink W, Pedersen UG, Andreasen AS, Buus L, Aslam TN, Winding RR, Schefold JC, Thorup SB, Iversen SA, Engstrøm J, Kjær MBN, Rasmussen BS, HOT-ICU Investigators. N Engl J Med. 2021 Jan 20.
Renal function adjusted D-dimer levels in critically ill patients with suspected thromboembolism.
Schefold JC, Gerber JL, Angehrn MC, Müller M, Messmer AS, Leichtle AB, Fiedler GM, Exadaktylos AK, Pfortmueller CA. Crit Care Med. 2020 Apr;48(4):e270-e276.
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