Publications Emilie Seydoux: ORCID 0000-0003-1021-4056 (https://orcid.org/my-orcid?orcid=0000-0003-1021-4056)
Publications Matthias Kopp: ORCID 0000-0003-1989-5492 (https://orcid.org/0000-0003-1989-5492)
2021
Impact of imposed social isolation and use of face masks on asthma course and mental health in pediatric and adult patients with recurrent wheeze and asthma. Maison N, Herbrüggen H, Schaub B, Schauberger C, Foth S, Grychtol R, Abdo M, Watz H, Nikolaizik W, Rabe KF, Kopp MV, Hansen G, von Mutius E, Bahmer T, Omony J; ALLIANCE study group. Allergy Asthma Clin Immunol. 2021 Sep 16;17(1):93. doi: 10.1186/s13223-021-00592-9. PMID: 34530911.
[Prevention of infections by influenza virus and respiratory syncytial virus after removal of the lockdown measures]. Huppertz HI, Kopp MV, Hübner J. Monatsschr Kinderheilkd. 2021;169(11):1072-1074. doi: 10.1007/s00112-021-01278-7. Epub 2021 Aug 17. PMID: 34421128.
Biologicals in childhood severe asthma: the European PERMEABLE survey on the status quo. Santos-Valente E, Buntrock-Döpke H, Abou Taam R, Arasi S, Bakirtas A, Lozano Blasco J, Bønnelykke K, Craiu M, Cutrera R, Deschildre A, Elnazir B, Fleming L, Frey U, Gappa M, Nieto García A, Skamstrup Hansen K, Hanssens L, Jahnz-Rozyk K, Jesenak M, Kerzel S, Kopp MV, Koppelman GH, Krivec U, MacLeod KA, Mäkelä M, Melén E, Mezei G, Moeller A, Moreira A, Pohunek P, Minić P, Rutjes NWP, Sammut P, Schwerk N, Szépfalusi Z, Turkalj M, Tzotcheva I, Ulmeanu A, Verhulst S, Xepapadaki P, Niggel J, Vijverberg S, Maitland-van der Zee AH, Potočnik U, Reinartz SM, van Drunen CM, Kabesch M. ERJ Open Res. 2021 Aug 16;7(3):00143-2021. doi: 10.1183/23120541.00143-2021. PMID: 34409097.
COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy. Weckmann M, Bahmer T, Sand JM, Rank Rønnow S, Pech M, Vermeulen C, Faiz A, Leeming DJ, Karsdal MA, Lunding L, Oliver BGG, Wegmann M, Ulrich-Merzenich G, Juergens UR, Duhn J, Laumonnier Y, Danov O, Sewald K, Zissler U, Jonker M, König I, Hansen G, von Mutius E, Fuchs O, Dittrich AM, Schaub B, Happle C, Rabe KF, van de Berge M, Burgess JK, Kopp MV; ALLIANCE Study Group as part of the German Centre for Lung Research (DZL). Eur Respir J. 2021 Dec 9;58(6):2003969. doi: 10.1183/13993003.03969-2020. PMID: 34326188
Striking Decrease of Enteroviral Meningitis in Children During the COVID-19 Pandemic. Stoffel L, Agyeman PKA, Keitel K, Barbani MT, Duppenthaler A, Kopp MV, Aebi C. Open Forum Infect Dis. 2021 Apr 8;8(6):ofab115. doi: 10.1093/ofid/ofab115. eCollection 2021 Jun. PMID: 34183977.
Allergen extract- and component-based diagnostics in children of the ALLIANCE asthma cohort. Skevaki C, Tafo P, Eiringhaus K, Timmesfeld N, Weckmann M, Happle C, Nelson PP, Maison N, Schaub B, Ricklefs I, Fuchs O, von Mutius E, Kopp MV, Renz H, Hansen G, Dittrich AM; ALLIANCE Study Group. Clin Exp Allergy. 2021 Oct;51(10):1331-1345. doi: 10.1111/cea.13964. PMID: 34128558.
COL4A3 expression in asthmatic epithelium depends on intronic methylation and ZNF263 binding. Nemani SSP, Vermeulen CJ, Pech M, Faiz A, Oliver BGG, van den Berge M, Burgess JK, Kopp MV, Weckmann M. ERJ Open Res. 2021 Jun 7;7(2):00802-2020. doi: 10.1183/23120541.00802-2020. PMID: 34109240.
Interobserver agreement in interpretation of chest radiographs for pediatric community acquired pneumonia: Findings of the pedCAPNETZ-cohort. Voigt GM, Thiele D, Wetzke M, Weidemann J, Parpatt PM, Welte T, Seidenberg J, Vogelberg C, Koster H, Rohde GGU, Härtel C, Hansen G, Kopp MV. Pediatr Pulmonol. 2021 Aug;56(8):2676-2685. doi: 10.1002/ppul.25528. PMID: 34076967.
Small Airway Dysfunction Links Asthma Severity with Physical Activity and Symptom Control. Abdo M, Trinkmann F, Kirsten AM, Pedersen F, Herzmann C, von Mutius E, Kopp MV, Hansen G, Waschki B, Rabe KF, Watz H, Bahmer T; Study Group. J Allergy Clin Immunol Pract. 2021 Sep;9(9):3359-3368.e1. doi: 10.1016/j.jaip.2021.04.035. PMID: 33930619.
Accelerated Dose Escalation with 3 Injections of an Aluminum Hydroxide-Adsorbed Allergoid Preparation of 6 Grasses Is Safe for Children and Adolescents with Moderate to Severe Allergic Rhinitis. Bovermann X, Ricklefs I, Vogelberg C, Klimek L, Kopp MV. Int Arch Allergy Immunol. 2021;182(6):524-534. doi: 10.1159/000512561. PMID: 33503610.
Cytokine levels in children and adults with wheezing and asthma show specific patterns of variability over time. Weckmann M, Thiele D, Liboschik L, Bahmer T, Pech M, Dittrich AM, Fuchs O, Happle C, Schaub B, Ricklefs I, Rabe KF, von Mutius E, Hansen G, König IR, Kopp MV; ALLIANCE Study Group. Clin Exp Immunol. 2021 Apr;204(1):152-164. doi: 10.1111/cei.13550. PMID: 33202033
Breath volatile organic compounds and inflammatory markers in adult asthma patients: negative results from the ALLIANCE cohort. Holz O, Waschki B, Watz H, Kirsten A, Abdo M, Pedersen F, Weckmann M, Fuchs O, Dittrich AM, Hansen G, Kopp MV, von Mutius E, Rabe KF, Hohlfeld JM, Bahmer T; ALLIANCE Study Group. Eur Respir J. 2021 Feb 11;57(2):2002127. doi: 10.1183/13993003.02127-2020. PMID: 33008938.
RNA-seq-based profiling of extracellular vesicles in plasma reveals a potential role of miR-122-5p in asthma. Bahmer T, Krauss-Etschmann S, Buschmann D, Behrends J, Watz H, Kirsten AM, Pedersen F, Waschki B, Fuchs O, Pfaffl MW, von Mutius E, Rabe KF, Hansen G, Kopp MV, König IR, Bartel S. Allergy. 2021 Jan;76(1):366-371. doi: 10.1111/all.14486. PMID: 32627209.
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies. Seydoux E, Wan YH, Feng J, Wall A, Aljedani S, Homad LJ, MacCamy AJ, Weidle C, Gray MD, Brumage L, Taylor JJ, Pancera M, Stamatatos L, McGuire AT. Cell Rep. 2021 Jul 20;36(3):109454. doi: 10.1016/j.celrep.2021.109454. PMID: 34289363
Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects. Jennewein MF, MacCamy AJ, Akins NR, Feng J, Homad LJ, Hurlburt NK, Seydoux E, Wan YH, Stuart AB, Edara VV, Floyd K, Vanderheiden A, Mascola JR, Doria-Rose N, Wang L, Yang ES, Chu HY, Torres JL, Ozorowski G, Ward AB, Whaley RE, Cohen KW, Pancera M, McElrath MJ, Englund JA, Finzi A, Suthar MS, McGuire AT, Stamatatos L. Cell Rep. 2021 Jul 13;36(2):109353. doi: 10.1016/j.celrep.2021.109353. PMID: 34237283.
mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection. Stamatatos L, Czartoski J, Wan YH, Homad LJ, Rubin V, Glantz H, Neradilek M, Seydoux E, Jennewein MF, MacCamy AJ, Feng J, Mize G, De Rosa SC, Finzi A, Lemos MP, Cohen KW, Moodie Z, McElrath MJ, McGuire AT. Science. 2021 Mar 25:eabg9175. doi: 10.1126/science.abg9175. PMID: 33766944.
Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation. Hurlburt NK, Seydoux E, Wan YH, Edara VV, Stuart AB, Feng J, Suthar MS, McGuire AT, Stamatatos L, Pancera M. Nat Commun. 2020 Oct 27;11(1):5413. doi: 10.1038/s41467-020-19231-9. PMID: 33110068.
2020
Multicentre feasibility of multiple-breath washout in preschool children with cystic fibrosis and other lung diseases. Stahl M, Joachim C, Kirsch I, Uselmann T, Yu Y, Alfeis N, Berger C, Minso R, Rudolf I, Stolpe C, Bovermann X, Liboschik L, Steinmetz A, Tennhardt D, Dörfler F, Röhmel J, Unorji-Frank K, Rückes-Nilges C, von Stoutz B, Naehrlich L, Kopp MV, Dittrich AM, Sommerburg O, Mall MA. ERJ Open Res. 2020 Oct 26;6(4):00408-2020. doi: 10.1183/23120541.00408-2020. PMID: 33263048.
Small airway dysfunction as predictor and marker for clinical response to biological therapy in severe eosinophilic asthma: a longitudinal observational study. Abdo M, Watz H, Veith V, Kirsten AM, Biller H, Pedersen F, von Mutius E, Kopp MV, Hansen G, Waschki B, Rabe KF, Trinkmann F, Bahmer T. Respir Res. 2020 Oct 21;21(1):278. doi: 10.1186/s12931-020-01543-5. PMID: 33087134.
Preterm birth and sustained inflammation: consequences for the neonate. Humberg A, Fortmann I, Siller B, Kopp MV, Herting E, Göpel W, Härtel C; German Neonatal Network, German Center for Lung Research and Priming Immunity at the beginning of life (PRIMAL) Consortium. Semin Immunopathol. 2020 Aug;42(4):451-468. doi: 10.1007/s00281-020-00803-2. PMID: 32661735.
Accelerated Dose Escalation with Three Injections of an Aluminum Hydroxide-Adsorbed Allergoid Preparation of Six Grasses Is Safe for Patients with Moderate to Severe Allergic Rhinitis. Kopp MV, Bovermann X, Klimek L. Int Arch Allergy Immunol. 2020;181(2):94-102. doi: 10.1159/000503684. PMID: 31865326.
Preclinical optimization of an enterotoxigenic Escherichia coli adjuvanted subunit vaccine using response surface design of experiments. Poncet D, Hessler C, Liang H, Gautheron S, Sergent M, Rintala ND, Seydoux E, Huang PD, Argilla D, Ruiz S, Heinrichs J, Maciel M Jr, Orr MT. NPJ Vaccines. 2020 Sep 11;5:83. doi: 10.1038/s41541-020-00228-w. PMID: 32983577.
Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation. Seydoux E, Homad LJ, MacCamy AJ, Parks KR, Hurlburt NK, Jennewein MF, Akins NR, Stuart AB, Wan YH, Feng J, Whaley RE, Singh S, Boeckh M, Cohen KW, McElrath MJ, Englund JA, Chu HY, Pancera M, McGuire AT, Stamatatos L. Immunity. 2020 Jul 14;53(1):98-105.e5. doi: 10.1016/j.immuni.2020.06.001. PMID: 32561270.
2019
Perspectives in allergen immunotherapy: 2019 and beyond. Pfaar O, Agache I, de Blay F, Bonini S, Chaker AM, Durham SR, Gawlik R, Hellings PW, Jutel M, Kleine-Tebbe J, Klimek L, Kopp MV, Nandy A, Rabin RL, van Ree R, Renz H, Roberts G, Salapatek AM, Schmidt-Weber CB, Shamji MH, Sturm GJ, Virchow JC, Wahn U, Willers C, Zieglmayer P, Akdis CA. Allergy. 2019 Dec;74 Suppl 108:3-25. doi: 10.1111/all.14077. PMID: 31872476.
PedCAPNETZ - prospective observational study on community acquired pneumonia in children and adolescents. Wetzke M, Kopp MV, Seidenberg J, Vogelberg C, Ankermann T, Happle C, Voigt G, Köster H, Illig T, Lex C, Schuster A, Panning M, Barten G, Rohde G, Welte T, Hansen G; pedCAPNETZ Study Group. BMC Pulm Med. 2019 Dec 9;19(1):238. doi: 10.1186/s12890-019-1013-5. PMID: 31818288.
Comparison of Six Different Allergen Extracts for Subcutaneous Specific Immunotherapy in Children: An Open-Labelled, Prospective, Controlled Observational Trial. Kopp MV, König IR, Friedrichs F, Umpfenbach HU, Niggemann B, Millner-Uhlemann M. Int Arch Allergy Immunol. 2019;180(4):284-290. doi: 10.1159/000503104. PMID: 31665735.
The TLR4 agonist adjuvant SLA-SE promotes functional mucosal antibodies against a parenterally delivered ETEC vaccine. Liang H, Poncet D, Seydoux E, Rintala ND, Maciel M Jr, Ruiz S, Orr MT. NPJ Vaccines. 2019 May 28;4:19. doi: 10.1038/s41541-019-0116-6. PMID: 31149350.
Reprogramming the adjuvant properties of aluminum oxyhydroxide with nanoparticle technology. Orr MT, Khandhar AP, Seydoux E, Liang H, Gage E, Mikasa T, Beebe EL, Rintala ND, Persson KH, Ahniyaz A, Carter D, Reed SG, Fox CB. NPJ Vaccines. 2019 Jan 3;4:1. doi: 10.1038/s41541-018-0094-0. PMID: 30622742.
